Stanoplex (also known as Stanozolol or Winstrol) is a 17-alpha-alkylated dihydrotestosterone (DHT) derivative with low androgenic properties but high anabolic effects. It was first developed in 1962 by the American global pharmaceutical company Sterling-Winthrop Laboratories to increase lymphocyte and CD8+ cell counts but to decrease CD4+ and CD3+ in postmenopausal women using it to treat osteoporosis. Stanozolol is now available for sale in two forms: tablets and injections. Stanoplex (stanozolol) is the second most common oral steroid, second only to metandienone in popularity. Stanozolol tablets have a short duration of action (about 9 hours) compared to injectable stanozolol. The injectable version of stanozolol differs from other injectable anabolic steroids in that it is an aqueous suspension of fine steroid particles rather than an oily solution of the esterified compound. For this reason, it has an unusual pharmacokinetics that does not follow the classical half-life. Instead, there is a sustained effect that gradually wanes.
Although stanozolol is a DHT-based compound, its activity is much milder than that androgen in nature. As a derivative of DHT, stanozolol cannot be converted to estradiol, so no aromatase inhibitors are required when taking it. As a result, stanozolol does not cause water retention. On the contrary, it has a diuretic effect. Thus, instead of a bulky look, Stanoplex creates a lean, quality look without excessive subcutaneous water retention. This makes it an excellent steroid for use in reduction cycles, when the main goal is to get rid of excess water and fat, as well as strongly pronounced, rigid muscle. Because of its properties, stanozolol is highly valued among athletes in strength/speed sports such as track and field. As far as bodybuilders are concerned, stanozolol has one interesting feature that is in demand among them. It lies in its profound ability to reduce levels of sex hormone-binding globulin (SHBG), which leads to increased effectiveness of other steroids in the same stack as it. In particular, it increases the amount of biologically active free testosterone circulating in the blood. For this reason, it is always recommended to use stanozolol in combination with testosterone. Another reason is the following: Stanoplex may be more prone than other anabolic steroids to increase tendon fragility. This is because of Stanoplex's ability to dry out joint fluid, which can lead to pain and joint damage. Also, both forms of stanozolol: tablets and injections - provoke adverse changes in cholesterol levels. Therefore, it is recommended to monitor the lipid profile of the body (blood tests) during the cycle.